| 產(chǎn)品編號 | bs-7642R |
| 英文名稱 | Rabbit Anti-AGTRAP antibody |
| 中文名稱 | 血管緊張素Ⅱ受體相關(guān)蛋白抗體 |
| 別 名 | Angiotensin Ⅱ receptor associated protein; Angiotensin Ⅱ type I receptor associated protein; ATI receptor associated protein; ATRAP; MGC29646; Type 1 angiotensin Ⅱ receptor associated protein; ATRAP_HUMAN. |
| 研究領(lǐng)域 | 心血管 細胞生物 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 17kDa |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AGTRAP: 31-90/159 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
AGTRAP (Angiotensin II receptor-associated protein) interacts with the angiotensin II type 1 receptor and negatively regulates type 1 angiotensin II receptor-mediated signaling, by regulating receptor internalisation as well as mechanisms of receptor desensitization such as phosphorylation. Function: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. Subunit: Interacts with GNB2L1/RACK1, and with the C-terminal region of AGTR1. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles. Tissue Specificity: Ubiquitous but more abundant in kidney, heart, pancreas and thyroid. SWISS: Q6RW13 Gene ID: 57085 Database links: Entrez Gene: 57085 Human Omim: 608729 Human SwissProt: Q6RW13 Human Unigene: 464438 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復(fù)方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關(guān)于肽鏈的設(shè)計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
