| 產(chǎn)品編號(hào) | bs-7585R |
| 英文名稱(chēng) | Rabbit Anti-BCL2 like 14 antibody |
| 中文名稱(chēng) | Bcl2樣凋亡蛋白14抗體 |
| 別 名 | Apoptosis facilitator Bcl 2 like 14 protein; Apoptosis facilitator Bcl 2 like protein 14; Apoptosis regulator Bcl G; Bcl2 L 14; BCL2 like 14 (apoptosis facilitator); BCL2 like 14; BCL2L14; BCLG; B2L14_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞凋亡 細(xì)胞類(lèi)型標(biāo)志物 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 37kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Bcl G/BCL2 like 14: 251-327/327 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Bcl-G is a novel pro-apoptotic member of the Bcl-2 family. The human Bcl-G gene encodes two proteins through alternative mRNA splicing, Bcl-G(L) (long) and Bcl-G(S) (short) consisting of 327 and 252 amino acids in length, respectively. Bcl-G(L) mRNA is expressed widely in adult human tissues, whereas Bcl-G(S) mRNA was found only in testis. Overexpression of Bcl-G(L) or Bcl-G(S) in cells induced apoptosis although Bcl-G(S) was far more potent than Bcl-G(L). Function: Plays a role in apoptosis. Subcellular Location: Cytoplasm. Isoform 1: Cytoplasm, cytosol. Note=Diffusely distributed throughout the cytosol. Isoform 2: Endomembrane system. Note=Predominantly localized to cytosolic organelles. Tissue Specificity: Isoform 1 is widely expressed. Isoform 2 is testis-specific. Post-translational modifications: Phosphorylated by MELK, leading to inhibit its pro-apoptotic function. Similarity: Belongs to the Bcl-2 family. SWISS: Q9BZR8 Gene ID: 79370 Database links:
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