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Rabbit Anti-IEX1  antibody (bs-6840R)  
~~~促銷代碼KT202411~~~
訂購熱線:400-901-9800
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-6840R
英文名稱 Rabbit Anti-IEX1  antibody
中文名稱 分化相關(guān)基因2蛋白/立即早期反應(yīng)蛋白抗體
別    名 IEX1; PRG1; Anti death protein; Differentiation dependent gene 2 protein; DIF 2; DIF2; Differentiation dependent gene 2; Differentiation dependent gene 2 protein; Differentiation-dependent gene 2 protein; Expressed in pancreatic carcinoma; GLY 96; GLY96; Gly96 mouse homolog of; IER 3; IER3; IEX 1; IEX 1L; IEX1_HUMAN; IEX1L; Immediate early protein GLY96; Immediate early response 3; Immediate early response 3 protein; Immediately early gene X 1; PACAP responsive gene 1; PACAP responsive gene 1 protein; PACAP-responsive gene 1 protein; PRG 1; Protein DIF 2; Protein DIF-2; Protein PRG1; Radiation-inducible immediate-early gene IEX-1.  
研究領(lǐng)域 腫瘤  細胞生物  發(fā)育生物學  信號轉(zhuǎn)導  干細胞  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein: 85-156/156 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008].

Function:
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival.

Subunit:
Interacts with the PPP2R5C-PP2A holoenzyme and ERK kinases; regulates ERK dephosphorylation.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the IER3 family.

SWISS:
P46695

Gene ID:
8870

Database links:

Entrez Gene: 8870 Human

Entrez Gene: 15937 Mouse

Omim: 602996 Human

SwissProt: P46695 Human

SwissProt: P46694 Mouse

Unigene: 730861 Human

Unigene: 76095 Human

Unigene: 25613 Mouse



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