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Rabbit Anti-Aquaporin 8  antibody (bs-6786R)  
~~~促銷(xiāo)代碼KT202411~~~
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產(chǎn)品編號(hào) bs-6786R
英文名稱(chēng) Rabbit Anti-Aquaporin 8  antibody
中文名稱(chēng) 水通道蛋白8抗體
別    名 AQP 8; AQP-8; AQP8; AQP8_HUMAN; Aquaporin 8; Aquaporin-8; Aquaporin8.  
Specific References  (7)     |     bs-6786R has been referenced in 7 publications.
[IF=7.675] Yimeng Fan. et al. Pingwei San Ameliorates Spleen Deficiency-Induced Diarrhea through Intestinal Barrier Protection and Gut Microbiota Modulation. ANTIOXIDANTS-BASEL. 2023 May;12(5):1122  IHC ;  Rat.  
[IF=6.107] Xiao-Hu Zhao. et al. Integrative analysis reveals marker genes for intestinal mucosa barrier repairing in clinical patients. ISCIENCE. 2023 May;:106831  WB ;  Human.  
[IF=5.279] Qi-Le Zuo. et al. Influences of Xylitol Consumption at Different Dosages on Intestinal Tissues and Gut Microbiota in Rats. J Agr Food Chem. 2021;XXXX(XXX):XXX-XXX  IHC ;  rat.  
[IF=5.165] Chenhong Lin. et al. Osmotic pressure induces translocation of aquaporin-8 by P38 and JNK MAPK signaling pathways in patients with functional constipation. DIGEST LIVER DIS. 2023 Feb;:  WB,IF ;  Human.  
[IF=3.414] Li X et al. Physicochemical properties and laxative effects of polysaccharides from Anemarrhena asphodeloides Bge. In loperamide-induced rats. J Ethnopharmacol. 2019 Aug 10;240:111961.  WB ;  Rat.  
[IF=2.299] Ferré-Dolcet L et al. Uterine and placental specific localization of AQP2 and AQP8 is related with changes of serum progesterone levels in pregnant queens. Theriogenology. 2019 Oct 1;142:149-157.  WB&IHF ;  queen.  
[IF=1.09] Wang, Wei, et al. "Expression of AQP5 and AQP8 in human colorectal carcinoma and their clinical significance." World journal of surgical oncology 10.1 (2012): 1-5.  IHC-P ;  Human.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  通道蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human,Rat (predicted: Mouse,Pig,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Aquaporin 8: 101-220/261 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Forms a water-specific channel; mercury-sensitive. plays a role in water transport across hepatocyte membranes [RGD, Feb 2006]

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed only in pancreas and colon.

Similarity:
Belongs to the MIP/aquaporin (TC 1.A.8) family.

SWISS:
O94778

Gene ID:
343

Database links:

Entrez Gene: 343 Human

Omim: 603750 Human

SwissProt: O94778 Human

Unigene: 176658 Human



產(chǎn)品圖片
Tissue/cell: human colon carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-AQP8/Aquaporin 8 Polyclonal Antibody, Unconjugated(bs-6786R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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