| 產(chǎn)品編號 | bs-6612R |
| 英文名稱 | Rabbit Anti-BMP15 antibody |
| 中文名稱 | 骨形態(tài)發(fā)生蛋白15抗體 |
| 別 名 | BMP 15; BMP-15; BMP15; BMP15_HUMAN; Bone morphogenetic protein 15; GDF 9B; GDF-9B; GDF9B; Growth/differentiation factor 9B; ODG2; POF4. |
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Specific References (2) | bs-6612R has been referenced in 2 publications.
[IF=2.586] G?k?e Nur Ar?k. et al. Melatonin effective to reduce the microscopic symptoms of polycystic ovary syndrome-related infertility: An experimental study. TISSUE CELL. 2023 Jan;:102015 IHC,WB ; Rat.
[IF=1.281] Pinar Kacamak. et al. The Effect of Isotretinoin on Oocyte Maturation in Adolescent Female Rats. Gynecol Obstet Inves. 2020;85(4):327-335 IHC ; Rat.
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| 研究領(lǐng)域 | 心血管 發(fā)育生物學(xué) 染色質(zhì)和核信號 信號轉(zhuǎn)導(dǎo) 干細(xì)胞 生長因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 14kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BMP15: 321-392/392 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The BMP15 protein is a member of the bone morphogenetic protein family which is part of the transforming growth factor beta superfamily. The transforming growth factor beta superfamily includes large families of growth and differentiation factors. It is thought that BMP15 may be involved in oocyte maturation and follicular development as a homodimer, or by forming heterodimers with a related protein, Gdf9. Function: May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. Subunit: Homodimer. But, in contrast to other members of this family, cannot be disulfide-linked. Subcellular Location: Secreted. DISEASE: Defects in BMP15 are the cause of ovarian dysgenesis type 2 (ODG2) [MIM:300510]; also known as X-linked hypergonadotropic ovarian dysgenesis or hypergonadotropic ovarian failure due to ovarian dysgenesis. Ovarian dysgenesis leads to ovarian failure and accounts for about half of the cases of primary amenorrhea. Defects in BMP15 are the cause of premature ovarian failure type 4 (POF4) [MIM:300510]. An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. Similarity: Belongs to the TGF-beta family. SWISS: O95972 Gene ID: 9210 Database links: Entrez Gene: 9210 Human Entrez Gene: 12155 Mouse Omim: 300247 Human SwissProt: O95972 Human SwissProt: Q9Z0L4 Mouse Unigene: 532692 Human Unigene: 42160 Mouse |
| 產(chǎn)品圖片 |
Sample:
A549(Human) Cell Lysate at 40 ug
Primary: Anti-BMP15 (bs-6612R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 14 kD
Observed band size: 14 kD
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