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Rabbit Anti-XAB2  antibody (bs-6080R)  
~~~促銷代碼KT202411~~~
訂購熱線:400-901-9800
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-6080R
英文名稱 Rabbit Anti-XAB2  antibody
中文名稱 XAB2蛋白抗體
別    名 0610041O14Rik; adapter protein ATH 55; Adapter protein ATH-55; Ath55; AV025587; Crn related protein kim1; crn-related protein kim1; DKFZp762C1015; HCNP; HCNP protein; HCRN; KIAA1177; NTC90; PP3898; Pre-mRNA-splicing factor SYF1; Protein HCNP; RNA splicing factor; SYF1; SYF1 homolog; SYF1 homolog, RNA splicing factor; SYF1_HUMAN; Xab2; XPA binding protein 2; XPA-binding protein 2.  
Specific References  (1)     |     bs-6080R has been referenced in 1 publications.
[IF=4.966] Shuiming Guo. et al. Pre‐ischemic renal lavage protects against renal ischemia‐reperfusion injury by attenuation of local and systemic inflammatory responses. Faseb J. 2020 Dec;34(12):16307-16318  WB ;  Rat.  
研究領域 腫瘤  細胞生物  免疫學  染色質(zhì)和核信號  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 100kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PBP/HCNP: 65-160/855 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 antibodies resulted in the inhibition of both transcription coupled repair and transcription.

Function:
Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.

Subunit:
Associates with RNA polymerase II, the TCR-specific proteins CKN1/CSA and ERCC6/CSB, and XPA. Identified in the spliceosome C complex.

Subcellular Location:
Nucleus (By similarity). Note=Detected in the splicing complex carrying pre-mRNA (By similarity).

Similarity:
Belongs to the crooked-neck family.
Contains 14 HAT repeats.

SWISS:
Q9HCS7

Gene ID:
56949

Database links:

Entrez Gene: 56949 Human

Entrez Gene: 67439 Mouse

Entrez Gene: 100525328 Pig

Entrez Gene: 245976 Rat

Omim: 610850 Human

SwissProt: Q9HCS7 Human

SwissProt: Q9DCD2 Mouse

SwissProt: Q99PK0 Rat

Unigene: 9822 Human

Unigene: 23739 Mouse

Unigene: 24921 Rat



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