| 產(chǎn)品編號 | bs-6077R |
| 英文名稱 | Rabbit Anti-NIT1 antibody |
| 中文名稱 | 腈水解酶1抗體 |
| 別 名 | NIT1; NIT1_HUMAN; Nitrilase 1; Nitrilase homolog 1. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 染色質(zhì)和核信號 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 36kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NBL1: 111-210/327 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2. Function: Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity). Subcellular Location: Cytoplasm. Mitochondrion. Tissue Specificity: Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the UPF0012 family. Contains 1 CN hydrolase domain. SWISS: Q86X76 Gene ID: 4817 Database links: Entrez Gene: 4817 Human Entrez Gene: 27045 Mouse Omim: 604618 Human SwissProt: Q86X76 Human SwissProt: Q8VDK1 Mouse Unigene: 146406 Human Unigene: 12915 Mouse Unigene: 270139 Mouse Unigene: 440362 Mouse Unigene: 64425 Rat |
