| 產(chǎn)品編號 | bs-5796R |
| 英文名稱 | Rabbit Anti-BCL2L10 antibody |
| 中文名稱 | BCL2樣10促凋亡蛋白抗體 |
| 別 名 | Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10 (apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; Diva; MGC129810; MGC129811; Nrh. |
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Specific References (3) | bs-5796R has been referenced in 3 publications.
[IF=5.572] Shaohua Hou. et al. Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors. Eur J Med Chem. 2021 Aug;220:113482 WB ; Human.
[IF=1.986] Huang,et al.Role of BCL2L10 in regulating buffalo (Bubalus bubalis) oocyte maturation.(2018) Theriogenology. 110:1-7. IHC-P + IF(ICC) ; Buffalo.
[IF=0.219] Wang,et al.Yisui shengxue granule, a traditional Chinese medicine compound preparation, can up-regulate the expression of GM-CSF and its receptor in mice bone marrow after irradiation.(2017) Biomedical Research. 28:. ICC ; Mouse.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞凋亡 腫瘤細(xì)胞生物標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 22kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BCL2L10: 101-194/194 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Function: Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. Subunit: Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1. Subcellular Location: Mitochondrion. Nucleus membrane. Tissue Specificity: Widely expressed in adult tissues. Similarity: Belongs to the Bcl-2 family. SWISS: Q9HD36 Gene ID: 10017 Database links: Entrez Gene: 10017 Human Omim: 606910 Human SwissProt: Q9HD36 Human Unigene: 283672 Human |
