| 產(chǎn)品編號(hào) | bs-5764R |
| 英文名稱(chēng) | Rabbit Anti-CIAPIN1 antibody |
| 中文名稱(chēng) | 細(xì)胞因子誘導(dǎo)凋亡抑制因子1 |
| 別 名 | Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞凋亡 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Pig,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 34kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CIAPIN1: 51-150/312 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1.
Function: May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitously expressed. Highly expressed in heart, liver and pancreas. Similarity: Belongs to the anamorsin family. SWISS: Q6FI81 Gene ID: 57019 Database links: Entrez Gene: 57019 Human Entrez Gene: 109006 Mouse Omim: 608943 Human SwissProt: Q6FI81 Human SwissProt: Q8WTY4 Mouse Unigene: 4900 Human Unigene: 27582 Mouse |
| 產(chǎn)品圖片 |
Sample: Heart (mouse) Cell Lysate at 40 ug
Primary: Anti- CIAPIN1(bs-5764R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 34kD
Observed band size: 36 kD
Sample: Hcclm3 (human)cell Lysate at 40 ug
Primary: Anti- CIAPIN1(bs-5764R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 34kD
Observed band size: 36 kD
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