產(chǎn)品編號(hào) | bs-5756R |
英文名稱(chēng) | Rabbit Anti-MPP6 antibody |
中文名稱(chēng) | 棕櫚酰化膜蛋白6抗體 |
別 名 | MAGUK p55 subfamily member 6 VELI associated MAGUK 1; MAGUK protein p55T; MPP6; Palmitoylated 6 MAGUK p55 subfamily member 6; PALS2; Protein associated with Lin7 2; VELI associated MAGUK 1; MPP6_HUMAN. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 細(xì)胞周期蛋白 激酶和磷酸酶 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 61kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human VAM1/MPP6: 431-540/540 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase promoting factor, or MPF. In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M phase phosphoproteins (MPPs, or MPHOSPHs) permit disassembly of interphase structures and generation of M phase enzymatic activities and structures. VAM1 or MPP6 is thought to be a nucleolus specific exosome co factor, required for its role in the maturation of 5.8S rRNA. Subunit: Interacts with CADM1 (By similarity). Interacts with the LIN7 proteins. Subcellular Location: Membrane; Peripheral membrane protein (By similarity). Tissue Specificity: Abundant in testis, brain, and kidney with lower levels detectable in other tissues. Similarity: Belongs to the MAGUK family. Contains 1 guanylate kinase-like domain. Contains 2 L27 domains. Contains 1 PDZ (DHR) domain. Contains 1 SH3 domain. SWISS: Q9NZW5 Gene ID: 51678 Database links: Entrez Gene: 51678 Human Entrez Gene: 56524 Mouse Omim: 606959 Human SwissProt: Q9NZW5 Human SwissProt: Q9JLB0 Mouse Unigene: 533355 Human |