產(chǎn)品編號(hào) | bs-4295R |
英文名稱 | Rabbit Anti-CDC40 antibody |
中文名稱 | 細(xì)胞分裂周期同源蛋白40抗體 |
別 名 | Cell division cycle 40 homolog; EH binding protein 3; Ehb3; Pre mRNA processing factor 17; PRP17; PRP17 homolog; PRPF17; PRP17_HUMAN; Pre-mRNA-processing factor 17; EH-binding protein 3; hPRP17. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 細(xì)胞周期蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 66kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CDC40: 481-579/579 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008] Function: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing. Subunit: Identified in the spliceosome C complex. Subcellular Location: Nucleus. Similarity: Contains 7 WD repeats. SWISS: O60508 Gene ID: 51362 Database links: Entrez Gene: 51362 Human Entrez Gene: 71713 Mouse Omim: 605585 Human SwissProt: O60508 Human SwissProt: Q9DC48 Mouse Unigene: 428147 Human Unigene: 46063 Mouse |