| 產(chǎn)品編號(hào) | bs-4273R |
| 英文名稱 | Rabbit Anti-PIH1D1 antibody |
| 中文名稱 | 核仁同源蛋白17抗體 |
| 別 名 | NOP17; Nucleolar protein 17 homolog; PIH1 domain containing 1; PIH1 domain containing protein 1; PIH1 domain-containing protein 1; PIH1D1; PIHD1_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞類型標(biāo)志物 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 32kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PIH1D1/NOP17: 91-190/290 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
PIH1D1 is a phylogenetically conserved protein essential for efficient processing of pre-rRNA through its association with a class of small nucleolar RNAs (snoRNAs) during ribosomal biogenesis. SnoRNAs are associated in ribonucleoprotein particles localized to the nucleolus. Nop17 is a 290 amnio acid unstable protein that is stabilized through an interaction with HSP 90å/∫. Nop17 interacts with a core box C/D snoRNP protein Nop58, indicating a function of Nop17 in mediating the nucleolar retention or proper assembly of the box C/D snoRNP. A mutation in NOP17 gene may lead to a temperature-sensitive phenotype along with delocalization of key Nop proteins that are essential for snoRNP assembly. Similarity: Belongs to the PIH1 family. SWISS: Q9NWS0 Gene ID: 55011 Database links: Entrez Gene: 55011 Human Omim: 611480 Human SwissProt: Q9NWS0 Human Unigene: 5245 Human
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