產(chǎn)品編號(hào) | bs-5131R |
英文名稱 | Rabbit Anti-GLO1 antibody |
中文名稱 | 乙二醛酶1抗體 |
別 名 | Aldoketomutase; GLOD1; Glx I; GLYI; Glyoxalase I; Ketone aldehyde mutase; Lactoyl glutathione lyase; S D lactoylglutathione methylglyoxal lyase; LGUL_HUMAN; glo1; glyoxalase domain containing 1; Ketone-aldehyde mutase; Methylglyoxalase. |
Specific References (1) | bs-5131R has been referenced in 1 publications.
[IF=4.49] Seyeon Oha et al. The attenuating effects of pyridoxamine on adipocyte hypertrophy and inflammation differ by adipocyte location. The Journal of Nutritional Biochemistry.2019 October, 72: 108173. WB&IHF ; Rat.
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研究領(lǐng)域 | 腫瘤 免疫學(xué) 糖尿病 內(nèi)分泌病 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Pig,Cow,Dog,GuineaPig,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 21kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GLO1: 101-184/184 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The enzyme encoded by GLO1 is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. GLO is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. Subunit: Homodimer. Similarity: Belongs to the glyoxalase I family. SWISS: Q04760 Gene ID: 2739 Database links: Entrez Gene: 2739 Human Entrez Gene: 109801 Mouse Omim: 138750 Human SwissProt: Q04760 Human SwissProt: Q9CPU0 Mouse Unigene: 268849 Human Unigene: 261984 Mouse |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GLO1) Polyclonal Antibody, Unconjugated (bs-5131R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.
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