| 產(chǎn)品編號(hào) | bs-2725R |
| 英文名稱(chēng) | Rabbit Anti-Mast Cell Tryptase antibody |
| 中文名稱(chēng) | 肥大細(xì)胞類(lèi)胰蛋白酶抗體 |
| 別 名 | Tryptase delta; Delta-tryptase; HmMCP-3-like tryptase III; Mast cell mMCP-7-like; Tryptase-3; TPSD1; MCP7L1; MMCP-7L; MCP7-LIKE; EC 3.4.21.59; MGC95428; TRYD; Tryptase3; alpha II; EC 3.4.21.59; Lung tryptase; Mast cell alpha II tryptase; Mast cell beta I tryptase; Mast cell protease 7; Mast cell protease II; MCP 7; MMCP 7; Pituitary tryptase; Skin tryptase; TPS 1; TPS1; TPS2; TPSAB1; TPSAB1 protein; TPSB1; Tryptase 1; Tryptase alpha 1; tryptase alpha I included; Tryptase alpha II; tryptase alpha II included; tryptase alpha included; tryptase alpha/beta 1; Tryptase beta 1; tryptase beta I included; Tryptase I; tryptase I included; Tryptase III; Tryptase skin; Tryptase beta-2; TRYB1_HUMAN; TRYB2_HUMAN; TRYD_HUMAN. |
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Specific References (1) | bs-2725R has been referenced in 1 publications.
[IF=2.311] Zhao Y et al. Interaction between regulatory T cells and mast cells via IL?9 and TGF?β productionOncol Lett.2020 Dec;20(6):360. IF ; Human.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 激酶和磷酸酶 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 23kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TPSD1: 171-242/242 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008] Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Subunit: Homotetramer. Subcellular Location: Secreted. Note=Released from the secretory granules upon mast cell activation. Tissue Specificity: Expressed in colon, lung, heart and synovial tissue. May be specific to mast cells. Similarity: Belongs to the peptidase S1 family. Tryptase subfamily. Contains 1 peptidase S1 domain. SWISS: Q15661 Gene ID: 7177 Database links: Entrez Gene: 7177 Human Entrez Gene: 100503895 Mouse Omim: 191080 Human SwissProt: Q15661 Human SwissProt: Q02844 Mouse Unigene: 405479 Human Unigene: 3301 Mouse Unigene: 10699 Rat |
