產(chǎn)品編號(hào) | bs-2656R |
英文名稱 | Rabbit Anti-LIR-6/LILRA1 antibody |
中文名稱 | 白細(xì)胞免疫球蛋白樣受體6抗體 |
別 名 | CD85 antigen-like family member I; CD85i; Leukocyte immunoglobulin-like receptor 6; Leukocyte immunoglobulin-like receptor subfamily A member 1; Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1; Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 soluble isoform; LILRA1; LIR-6; LIR6; LIRA1_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 52kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LIR6: 401-489/489 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] Function: May act as receptor for class I MHC antigens. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Detected in monocytes and B-cells. Similarity: Contains 4 Ig-like C2-type (immunoglobulin-like) domains. SWISS: O75019 Gene ID: 11024 Database links: Entrez Gene: 11024 Human Omim: 604810 Human SwissProt: O75019 Human Unigene: 710507 Human |