產(chǎn)品編號(hào) | bs-2565R |
英文名稱(chēng) | Rabbit Anti-Ly75 antibody |
中文名稱(chēng) | 淋巴細(xì)胞抗原75(CD205)抗體 |
別 名 | LY75_HUMAN; Lymphocyte antigen 75; CD205; CLEC13B; Ly-75; C-type lectin domain family 13 member B; DEC-205; gp200-MR6; |
研究領(lǐng)域 | 腫瘤 細(xì)胞類(lèi)型標(biāo)志物 b-淋巴細(xì)胞 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Cow,Dog,GuineaPig) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 195kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Ly75: 601-700/1722 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Predicted to enable signaling receptor activity. Predicted to be involved in immune response and inflammatory response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Function: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. Post-translational modifications: N-glycosylated. Similarity: Contains 10 C-type lectin domains. Contains 1 fibronectin type-II domain. Contains 1 ricin B-type lectin domain. SWISS: O60449 Gene ID: 4065 Database links: Entrez Gene: 4065 Human Entrez Gene: 17076 Mouse SwissProt: O60449 Human SwissProt: Q60767 Mouse |