產(chǎn)品編號 | bs-1939R |
英文名稱 | Rabbit Anti-ZNF474/ZFP106 antibody |
中文名稱 | 鋅指蛋白474抗體 |
別 名 | zinc finger protein; ZFP106; DKFZp451A239; FLJ34610; FLJ45841; SH3 domain binding protein 3; SH3BP3; Zfp 106; Zinc finger protein 106 homolog (mouse); Zinc finger protein 106 homolog; Zinc finger protein 474; ZNF474. |
研究領(lǐng)域 | 細(xì)胞生物 染色質(zhì)和核信號 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 207kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF474: 701-800/1883 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
ZFP106 is a new candidate transcription factor. It contains 2 C2H2-type zinc fingers and 6 WD repeats. May play a role in modulating tissue specificity to insulin (isoform 3). Widely expressed, including lymphocytes.Isoform 3 is most abundant in insulin-sensitive tissues such as skeletal muscle, heart, fat, kidney and liver. Expression is regulated by insulin (isoform 3). Subunit: Interacts with HPV type 6 protein E6. Does not interact significantly with E6 proteins from HPV types 11, 16, or 18. Interacts, via the Pro-rich regions, with the EVH1 domains of ENAH, EVL and VASP. Interacts with the first LIM domain of TES. Subcellular Location: Nucleus, nucleolus. Similarity: Contains 2 C2H2-type zinc fingers. Contains 6 WD repeats. SWISS: Q9H2Y7 Gene ID: 64397 Database links: Entrez Gene: 64397 Human SwissProt: Q9H2Y7 Human Unigene: 511143 Human |