產(chǎn)品編號(hào) | bs-1909R |
英文名稱 | Rabbit Anti-Telomerase Binding Protein, P23 antibody |
中文名稱 | 端粒酶結(jié)合蛋白P23抗體 |
別 名 | Telomerase Binding Protein,P23; Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; cPGES; Telomerase-binding protein p23; Hsp90 co-chaperone; Progesterone receptor complex p23; PTGES3; P23; TEBP; TEBP_HUMAN. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Rat (predicted: Mouse,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 18kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Telomerase Binding Protein, P23: 31-130/160 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family. Function: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Subunit: Binds to telomerase and to the progesterone receptor. Subcellular Location: Cytoplasm. Similarity: Belongs to the p23/wos2 family. Contains 1 CS domain. SWISS: Q15185 Gene ID: 10728 Database links: Entrez Gene: 10728 Human Entrez Gene: 100043508 Mouse Entrez Gene: 100048119 Mouse Entrez Gene: 56351 Mouse Omim: 607061 Human SwissProt: Q15185 Human SwissProt: Q9R0Q7 Mouse Unigene: 50425 Human Unigene: 305816 Mouse Unigene: 2344 Rat Telomerase Binding Protein,P23是一種端粒酶結(jié)合蛋白。 |
產(chǎn)品圖片 |
Sample:
Jurkat(Human) Cell Lysate at 30 ug
Primary: Anti-Telomerase Binding Protein, P23 (bs-1909R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 18 kD
Observed band size: 18 kD
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Telomerase Binding Protein, P23 Antibody, Unconjugated(bs-1909R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
|