產(chǎn)品編號 | bs-1773R |
英文名稱 | Rabbit Anti-Follistatin antibody |
中文名稱 | 促卵泡激素抑釋素/卵泡抑素抗體 |
別 名 | Activin binding protein; FS; Follistatin; Activin-binding protein; FS; fst; FST_HUMAN; Human follistatin gene; follistatin isoform FST344 precursor; FST344; follistatin isoform FST317 precursor; FST317; FST_HUMAN. |
研究領(lǐng)域 | 免疫學(xué) 生長因子和激素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse,Rat (predicted: Pig,Sheep,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 38kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Follistatin: 151-250/344 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. There is evidence linking polycystic ovary syndrome and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. It specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone. Subunit: Monomer (Potential). Subcellular Location: Secreted. Tissue Specificity: Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. Similarity: Contains 3 follistatin-like domains. Contains 3 Kazal-like domains. Contains 1 TB (TGF-beta binding) domain. SWISS: P19883 Gene ID: 10468 Database links: Entrez Gene: 396119 Chicken Entrez Gene: 10468 Human Entrez Gene: 14313 Mouse Omim: 136470 Human SwissProt: Q90844 Chicken SwissProt: P19883 Human SwissProt: P47931 Mouse Unigene: 9914 Human Unigene: 4913 Mouse Unigene: 162557 Rat 促卵泡激素抑釋素/卵泡抑素: 腦垂體細(xì)胞分泌的一種糖蛋白??膳c促卵泡激素釋放素/紅細(xì)胞分化因子發(fā)生特異結(jié)合,抑制腦垂體分泌促卵泡激素。 |
產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Pituitary tissue lysates
Lane 2: Mouse Placenta tissue lysates
Lane 3: Rat Pituitary tissue lysates
Lane 4: Rat Placenta tissue lysates
Lane 5: Rat Breast tissue lysates
Primary: Anti-Follistatin (bs-1773R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 47 kD
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