產(chǎn)品編號(hào) | bs-1314R |
英文名稱 | Rabbit Anti-Oxytocin R antibody |
中文名稱 | 催產(chǎn)素受體(縮宮素受體)抗體 |
別 名 | OXYR_HUMAN; Oxytocin receptor; OXTR; OTR1; OT-R; OTR; OT R; OTR 1; OXT R; |
Specific References (12) | bs-1314R has been referenced in 12 publications.
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研究領(lǐng)域 | 神經(jīng)生物學(xué) 生長因子和激素 細(xì)胞膜受體 內(nèi)分泌病 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse,Rat (predicted: Pig,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 43kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse oxytocin receptor: 325-388/388 <Cytoplasmic> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
he protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008] Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. SWISS: P97926 Gene ID: 18430 Database links: Entrez Gene: 5021 Human Entrez Gene: 18430 Mouse Omim: 167055 Human SwissProt: P30559 Human SwissProt: P97926 Mouse SwissProt: Q28756 Sheep Unigene: 2820 Human Unigene: 333310 Mouse Unigene: 6841 Rat OTR在人的子宮平滑肌細(xì)胞膜上有縮宮素受體,縮宮素引起子宮收縮的機(jī)制可能是通過激活縮宮素受體而實(shí)現(xiàn)的。經(jīng)研究發(fā)現(xiàn),縮宮素受體在外周組織和中樞神經(jīng)系統(tǒng)內(nèi)均有分布??s宮素與不同組織、細(xì)胞上的縮宮素受體結(jié)合,通過多種信號(hào)轉(zhuǎn)導(dǎo)途徑而發(fā)揮作用。 |
產(chǎn)品圖片 |
Sample:
Brain (Mouse) Lysate at 40 ug
Primary: Anti-Oxytocin R (bs-1314R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kD
Observed band size: 53 kD
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