| 產(chǎn)品編號 | bs-1139R |
| 英文名稱 | Rabbit Anti-Somatostatin Receptor 5 antibody |
| 中文名稱 | 生長抑素受體5抗體 |
| 別 名 | somatostatin receptor 5; SS5R; Somatostatin receptor subtype 5; Somatostatin receptor type 5; SS 5R; SS5 R; SST R5; SSTR 5; SSTR5; SS-5-R; SS5-R; SS5R; SSR5_HUMAN. |
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Specific References (1) | bs-1139R has been referenced in 1 publications.
[IF=1.616] Sato A et al. Protein expression of somatostatin receptor 2, somatostatin receptor 5 and dopamine D2 receptor in normal pituitary gland and ACTH-secreting pituitary adenoma in dogs.Res Vet Sci. 2018 Aug;119:61-66. IF ; Dog.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞膜受體 G蛋白偶聯(lián)受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SSTR5: 201-300/364 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010] Function: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P35346 Gene ID: 6755 Database links: Entrez Gene: 6755 Human Entrez Gene: 20609 Mouse Omim: 182455 Human SwissProt: P35346 Human SwissProt: O08858 Mouse Unigene: 449840 Human Unigene: 728117 Human Unigene: 353282 Mouse Unigene: 91342 Rat SSTR5為G-蛋白偶聯(lián)的細(xì)胞膜受體,SSTR5的表達(dá)與腫瘤的分布、發(fā)生和發(fā)展中起重要作用。 |
