| 產(chǎn)品編號(hào) | bs-0743R |
| 英文名稱 | Rabbit Anti-CTGF antibody |
| 中文名稱 | 結(jié)締組織生長(zhǎng)因子抗體 |
| 別 名 | CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN. |
 |
Specific References (13) | bs-0743R has been referenced in 13 publications.
|
| 研究領(lǐng)域 | 心血管 免疫學(xué) 生長(zhǎng)因子和激素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse,Rat (predicted: Human,Pig,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 36kDa |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CTGF: 221-349/349 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]. Function: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Subunit: Monomer. Subcellular Location: Secreted, extracellular space, extracellular matrix. Secreted. Tissue Specificity: Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. Similarity: Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain. SWISS: P29279 Gene ID: 1490 Database links: Entrez Gene: 1490 Human Omim: 121009 Human SwissProt: P29279 Human SwissProt: P29268 Mouse Unigene: 410037 Human Unigene: 390287 Mouse 生長(zhǎng)因子和激素（ Growth Factor and Hormones） 結(jié)締組織生長(zhǎng)因子（CTGF）是調(diào)節(jié)細(xì)胞增生、分化和細(xì)胞外基質(zhì)形成的重要效應(yīng)分子,可調(diào)節(jié)機(jī)體有關(guān)組織、細(xì)胞生長(zhǎng)并與纖維化發(fā)生密切相關(guān)的一種因子，因而在肌體的各類創(chuàng)傷修復(fù)過(guò)程中具有重要的生理學(xué)意義。 |
