| 產(chǎn)品編號 | bs-0385R |
| 英文名稱 | Rabbit Anti-ARC antibody |
| 中文名稱 | 即刻早期基因ARC抗體 |
| 別 名 | ARG3.1; Arc; Arg 3.1; Activity regulated cytoskeletal associated protein; Activity regulated cytoskeletal protein; Activity-regulated cytoskeleton-associated protein; Activity regulated cytoskeletal-associated protein; ARC/ARG3.1; Activity-regulated gene 3.1 protein homolog; Activity regulated gene 3.1 protein homolog; Arg3.1; KIAA0278; ARC_HUMAN; growth factor ARC. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Rat (predicted: Mouse,Rabbit,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,Flow-Cyt=1μg /test,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 45kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ARC: 101-200/396 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Activity-regulated cytoskeleton-associated protein (ARC)in the brain and learning and memory, researchers believe: ARC protein is by strengthening the function of synaptic links in order to save the memory, including learning and memory and emotion. At present, the scientists will also Activity-regulated cytoskeleton-associated protein used to take drugs addiction. Function: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. Subunit: Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2. Subcellular Location: Cytoplasm, cytoskeleton. Endosome. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse. Similarity: Belongs to the ARC/ARG3.1 family. SWISS: Q7LC44 Gene ID: 23237 Database links: Entrez Gene: 23237 Human Entrez Gene: 11838 Mouse Omim: 605235 Human SwissProt: Q7LC44 Human SwissProt: Q9WV31 Mouse Unigene: 40888 Human Unigene: 741621 Human Unigene: 25405 Mouse Unigene: 10086 Rat 該蛋白與大腦的學(xué)習(xí)記憶有關(guān)，研究人員認(rèn)為：是ARC蛋白通過加強(qiáng)了突觸的聯(lián)系功能從而儲存了這些記憶，包括情感和學(xué)習(xí)記憶。 目前，科學(xué)家也將該蛋白用于吸食毒品成癮性的研究。 |
| 產(chǎn)品圖片 |
Sample:
Brain (Rat) Lysate at 40 ug
Brain (Mouse) Lysate at 40 ug
Primary: Anti-ARC (bs-0385R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 45 kD
Cell: A549
Concentration:1:100
Host/Isotype:Rabbit/IgG
Flow cytometric analysis of primary antibody (Cat#: bs-0385R) on A549(green) compared with isotype control in the absence of primary antibody (blue) followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG(H+L) secondary antibody .
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